http://www.dunlopmotorcycle.com/infocenter_tiretips.asp?id=13#tip
That's the best answer for your safety.
I'm a tight son of a ____. Always was. I have run tubes in all my tires, even on cast rims. I always carried a patch kit too. I never worried about safety much. The hole on the tire was left there. Taking the tire off, even just one side, is a b*tch on the side of the road.
Good thing flats don't happen often.
When I got the new bike last year, I got the road hazard package. If I get a flat, I'll just call HD. Their problem, I paid for it(still don't know why).
BTW, Fix -A-Flat does not work on tubes if you have spoked wheels. BTDT. Besides, it says on the can: "do not use in motorcycle tires". Wonder why?